The story takes place in the fictional town of Wentworth, Ohio, a typical suburban community. On Poplar Street, an autistic boy named Seth has gained the power to control reality through the help of a being known as Tak. Soon, Poplar Street begins to change shape, transforming from a quiet suburb into a wild west caricature based on what Seth has seen on his television. Meanwhile, the other residents of the street are being attacked by the many beings that Seth's imagination is creating, due to Tak's control over them. These residents are forced to work together to stop Seth and Tak from completely transforming the world around them and stop Tak before he kills anyone else. The Regulators was published at the same time as its mirror novel, Desperation.
Ralph Carver sticks out his tongue and makes a sound like a wasp caught in a mayonnaise jar. What a polite little animal it is, the young woman with the tu-tone hair thinks. 'I'm Cynthia Smith,' she says, extending her hand over the counter to the girl. 'Always a Cynthia and never a Cindy. Can you remember that?' The girl nods, smiling. 'And I'm always an Ellie, never a Margaret.'
Peter Jackson wears a t-shirt with Mr. Smiley-Smile on it while talking with Cary Ripton.
'Yo, Gary!' Peter Jackson says, pulling up beside him. He's wearing faded jeans and a tee-shirt with a big yellow smile-face on it. HAVE A NICE DAY! Mr Smiley-Smile is saying. 'How's it going, bad boy?'
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